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Search Results for " Cholinesterase (ChE) "

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阻害剤

天然化合物

カタログ番号	製品名	別名	ターゲット
T7891	Ipidacrine	NIK‐247	Others
	Ipidacrine (NIK‐247) (NIK‐247) is an Antidementia Agent		Others
T14194	β-NETA	α-NETA	AChE
	β-NETA (α-NETA) is a stable, noncompetitive, slowly reversible choline acetyltransferase (ChAT) inhibitor with an IC50 of 9 μM and is a potent chemokine-like receptor-1 (CMKLR1) antagonist. β-NETA has anti-cancer activit...		AChE
T19084	1-Naphthyl acetate		AChE
	1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages. 1-Naphthyl acetate is a potent chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity....		AChE
T9989	AChE-IN-27		Others
	AChE-IN-27 is a small molecule used for high-throughput assays.		Others
T7640	Aldicarb sulfone		AChE
	Aldicarb sulfone is a cholinesterase inhibitor .		AChE
T7114	GALANTHAMINONE	(-)-Narwedine,Narwedin	AChE
	Galanthaminone ((-)-Narwedine) is a cholinesterase (AChE) inhibitor, is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments.		AChE
T21825	TAE-1		Beta Amyloid , AChE
	TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.		Beta Amyloid , AChE
T0713	Drofenine hydrochloride	Hexahydroadiphenine hydrochloride	AChE
	Drofenine hydrochloride (Hexahydroadiphenine hydrochloride) is an effective competitive inhibitor of BChE (Ki value: 3 uM).		AChE
T1635	Fenchlorphos	Ronnel,Dermafos	AChE , Parasite
	Fenchlorphos (Dermafos) is a cholinesterase inhibitor, used as an insecticide.		AChE , Parasite
T20812	Azamethiphos		AChE
	Azamethiphos, an organothiophosphate insecticide, is used in Atlantic salmon fish farming to control parasites.		AChE
T0229	Rivastigmine	SDZ-ENA 713,S-Rivastigmine,Exelon	AChE
	Rivastigmine (Exelon) is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease.		AChE
T0780	Pyridostigmine bromide	Mestinon	AChE
	Pyridostigmine bromide (Mestinon) is a cholinesterase inhibitor with a slightly longer duration of action than NEOSTIGMINE. It is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.		AChE
T7213	Demecarium bromide	BC-48	AChE
	Demecarium bromide (BC-48) is a potent cholinesterase inhibitor,and is treatment glaucoma agent.		AChE
T1628	Rivastigmine tartrate	SDZ-ENA 713,ENA 713	AChR , AChE
	Rivastigmine tartrate (SDZ-ENA 713) is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON...		AChR , AChE
T0204	Protriptyline hydrochloride	Protriptyline HCl	5-HT Receptor , AChE
	Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochloride (Protriptyline HCl) blocks the re-uptake of norepineph...		5-HT Receptor , AChE
T2571	Benactyzine hydrochloride	Neuroleptone,Tranquilline,Amitakon	AChR , AChE
	Benactyzine hydrochloride (Neuroleptone) is a centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in research to investigate the role of cholinergic systems on beh...		AChR , AChE
T21439	Tacrine	CS 12602,Tacrinum,Tetrahydroaminocrine	AChR
	Tacrine (CS 12602) is an indirect cholinergic agonist and centrally acting anticholinesterase. It is approved for the treatment of Alzheimer's disease.		AChR
T7041	Donepezil	E2020,Donepezilo,Aricept	AChE
	Donepezil (Aricept) is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE). It can be used for the treatment of mild to moderate dementia of the Alzheimer's type.		AChE
T4466	Pitofenone hydrochloride	Baralgin Ketone Hydrochloride,Pitophenone hydrochloride	AChE
	Pitofenone hydrochloride (Pitophenone hydrochloride), a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively.		AChE
T22545	Acephate	acetylphosphoramidothioicacido,s-dimethylester,Ortran,Orthene,Acetamidophos,chevronorthene	AChE
	Acephate (Orthene) is an anticholinesterase insecticide with a weak inhibitory effect on AChE in rats, but it can effectively inhibit AChE in cockroaches.		AChE
T1072	Loxeen	Pridinol methanesulfonate	AChR
	Loxeen (Pridinol methanesulfonate) is used as an anticholinergic and as an antiparkinsonian agent.		AChR
T2191	Tacrine hydrochloride (hydrate)	Tacrine,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine	AChR , AChE
	Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and i...		AChR , AChE
T1612	Neostigmine methyl sulfate	Normastigmin,Hodostin,Syntostigmin	AChR , AChE
	Neostigmine methyl sulfate (Syntostigmin) is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier, used in the treatment of myasthenia gravis.		AChR , AChE
T2227	Hemicholinium 3	Hemicholinium-3,Hemicholine	Others , AChE
	Hemicholinium 3 is a potent and selective choline uptake blocker.		Others , AChE
T7465	4-Methylbenzylidene camphor	Enzacamene,4-MBC	AChE
	4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations ,specifically UV B radiation, also has estrogenic activities.		AChE
T6478	Donepezil Hydrochloride	Aricept,BNAG,E2020,Donepezil HCl	AChR , AChE
	Donepezil HCl(Aricept) is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM).		AChR , AChE
T1552	Itopride hydrochloride	HSR803,Ganaton	Dopamine Receptor , AChE
	Itopride hydrochloride (Ganaton) is an AChE and D2DR inhibitor.		Dopamine Receptor , AChE
T7002	Trihexyphenidyl hydrochloride	Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride	AChR
	Trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is an antiparkinsonian agent of the antimuscarinic class.		AChR
T1111	Pralidoxime Chloride	2-PAM chloride,2-Pyridinealdoxime methochloride,2-PAM (chloride)	AChE
	Pralidoxime Chloride (2-PAM chloride) is a useful agent in the treatment of organophosphate poisoning. Pralidoxime binds to organophosphate-inactivated acetylcholinesterase, used to combat poisoning by organophosphates o...		AChE
T2319	Acotiamide monohydrochloride trihydrate	Acotiamide hydrochloride,YM-443 HCl,Z-338 HCl	AChE
	Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamid...		AChE
T20539	Pirimiphos-methyl	R 33986,AI3-27699,Caswell No. 334B,PP511,Actelic	AChE , Parasite
	Pirimiphos-methyl (AI3-27699) is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, moths, sn...		AChE , Parasite
T13446	(S)-Rivastigmine D6 tartrate	(R)-Rivastigmine D6 tartrate	AChE
	(S)-Rivastigmine D6 tartrate is the deuterium labeled (S)-Rivastigmine, and is an inhibitor of cholinesterase.		AChE
T36795	Donepezil N-oxide
	Donepezil N-oxide is an active metabolite of the acetylcholinesterase inhibitor donepezil . Donepezil N-oxide inhibits cholinesterase (ChE) activity in human erythrocytes in a concentration-dependent manner, exhibiting 4...
T38740	Rivastigmine carbamate impurity	3-Nitrophenyl ethyl(methyl)carbamate
	Rivastigmine carbamate impurity (3-Nitrophenyl ethyl(methyl)carbamate) is a byproduct found in Rivastigmine, which is recognized as a powerful and orally active inhibitor of cholinesterase (ChE). Specifically, Rivastigmi...
T80100	Ovotransferrin (328-332)		Angiotensin-converting Enzyme (ACE)
	Ovotransferrin (328-332), with an IC50 of 20 μM, exhibits protective activity against hypertension by inhibiting the Angiotensin-Converting Enzyme (ACE) and also displays anti-Cholinesterase (ChE) activity, suggesting a ...		Angiotensin-converting Enzyme (ACE)
T78905	AChE-IN-29
	AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electric eel acetylcholinesterase (eeAChE), and equine butyrylcholinest...
T61454	α-NETA
	α-NETA is a potent and noncompetitive choline acetyltransferase (ChA) inhibitor with an IC 50 of 9 μM. α-NETA is a potent ALDH1A1 ( IC 50 =0.04 μM) and chemokine-like receptor-1 (CMKLR1) antagonist. α-NETA weakly inhibit...

Compounds

Synonym: (-)-Narwedine,Narwedin

Target: Beta Amyloid, AChE

Drofenine hydrochloride

T0713

Synonym: Hexahydroadiphenine hydrochloride

Target: AChE

Fenchlorphos

T1635

Synonym: Ronnel,Dermafos

Target: AChE, Parasite

Synonym: SDZ-ENA 713,S-Rivastigmine,Exelon

Target: AChE

Pyridostigmine bromide

Rivastigmine tartrate

T1628

Synonym: SDZ-ENA 713,ENA 713

Target: AChR, AChE

Protriptyline hydrochloride

T0204

Synonym: Protriptyline HCl

Target: 5-HT Receptor, AChE

Benactyzine hydrochloride

T2571

Synonym: Neuroleptone,Tranquilline,Amitakon

Target: AChR, AChE

Tacrine

T21439

Synonym: CS 12602,Tacrinum,Tetrahydroaminocrine

Target: AChR

Donepezil

T7041

Synonym: E2020,Donepezilo,Aricept

Target: AChE

Pitofenone hydrochloride

T4466

Synonym: Baralgin Ketone Hydrochloride,Pitophenone hydrochloride

Target: AChE

Acephate

T22545

Synonym: acetylphosphoramidothioicacido,s-dimethylester,Ortran,Orthene,Acetamidophos,chevronorthene

Target: AChE

Loxeen

T1072

Synonym: Pridinol methanesulfonate

Target: AChR

Tacrine hydrochloride (hydrate)

T2191

Synonym: Tacrine,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine

Target: AChR, AChE

Neostigmine methyl sulfate

T1612

Synonym: Normastigmin,Hodostin,Syntostigmin

Target: AChR, AChE

Hemicholinium 3

T2227

Synonym: Hemicholinium-3,Hemicholine

Target: Others, AChE

4-Methylbenzylidene camphor

T7465

Synonym: Enzacamene,4-MBC

Target: AChE

Donepezil Hydrochloride

T6478

Synonym: Aricept,BNAG,E2020,Donepezil HCl

Target: AChR, AChE

Itopride hydrochloride

T1552

Synonym: HSR803,Ganaton

Target: Dopamine Receptor, AChE

Trihexyphenidyl hydrochloride

T7002

Synonym: Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride

Target: AChR

Pralidoxime Chloride

T1111

Synonym: 2-PAM chloride,2-Pyridinealdoxime methochloride,2-PAM (chloride)

Target: AChE

Acotiamide monohydrochloride trihydrate

T2319

Synonym: Acotiamide hydrochloride,YM-443 HCl,Z-338 HCl

Target: AChE

Pirimiphos-methyl

T20539

Synonym: R 33986,AI3-27699,Caswell No. 334B,PP511,Actelic

Target: AChE, Parasite

(S)-Rivastigmine D6 tartrate

T13446

Synonym: (R)-Rivastigmine D6 tartrate

Rivastigmine carbamate impurity

T38740

Synonym: 3-Nitrophenyl ethyl(methyl)carbamate

Target:

Ovotransferrin (328-332)

T80100

Synonym:

Target: Angiotensin-converting Enzyme (ACE)

カタログ番号	製品名	別名	ターゲット
TN1091	Dehydronuciferine		AChE
	Dehydronuciferine is isolated from the leaves of Nelumbo nucifera Gaertn. Dehydronuciferine shows inhibitory of acetylcholinesterase with the IC50 of 25 ug/mL.		AChE
T3852	Rhodiosin		Antioxidant , AChE
	Rhodiosin is a compound with antioxidant activity.		Antioxidant , AChE
TN1011	Rhodionin		P450 , AChE
	Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administered drugs; they can significantly suppress the elevation of ...		P450 , AChE
T13301	Violanthin		AChE
	Violanthin is a natural product isolated from the aerial parts of Piper bavinum and inhibits acetylcholinesterase (AChE) (IC50: 79.80 μM). It has potent antioxidant and antibacterial activities.		AChE
T2846	Isoimperatorin		Antibacterial , AChE
	Isoimperatorin is an anti-inflammatory agent, exhibits significant inhibitory effects on acetylcholinesterase (AChE).		Antibacterial , AChE
TN1858	Leptomerine		AChE
	Leptomerine (IC50 = 2.5 mM) shows potent anticholinesterasic activity.		AChE
T5855	Edrophonium chloride		AChE
	Edrophonium chloride is an acetylcholinesterase (AChE) inhibitor that is known to prevent the breakdown of the neurotransmitter acetylcholine by binding specifically to its catalytic site.		AChE
T5S2361	Epiberberine		ERK , Beta-Secretase , MEK , BACE , AMPK , AChR , AChE
	1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/ERK1/2 and AMPKα/Akt pathways during 3T3-L1 adipocyte diffe...		ERK , Beta-Secretase , MEK , BACE , AMPK , AChR , AChE
TN1589	Dihydrowithaferin A		AChE
	Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prevent or decrease the growth of tumors.		AChE
T13469	(±)-Huperzine A		AChE
	(±)-Huperzine A is an active Lycopodium alkaloid extracted from traditional Chinese herbs. (±)-Huperzine A is a selective and reversible inhibitor of AChE and can be used in studies about the treatment of Alzheimer's dis...		AChE
T5S1408	Pteryxin	(+)-Pteryxin	Others , AChE
	(+)-Pteryxin ((+)-Pteryxin) has muscle-relaxant props. (+)-Pteryxin shows hepatoprotective and nitric oxide prodn. inhibitory activity.		Others , AChE
TN1899	Lycoramine		AChE
	Lycoramine is a natural product isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor		AChE
T13681	Epi-galantamine		AChE
	Epi-galantamine, a diastereomer of galantamine, is an alkaloid extracted from the bulbs and flowers of the Caucasian snowdrop (Galanthus woronowii). It acts as an AChE inhibitor, featuring an EC50 of 45.7 μM.		AChE
T4S1725	Galanthamine	Galantamine	Apoptosis , AChE
	Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.		Apoptosis , AChE
TN1786	Isomerazin	Isomeranzin	ERK , NF-κB , AChE
	Isomerazin (Isomeranzin) has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathway.		ERK , NF-κB , AChE
T11366	Garcinol		Apoptosis , Endogenous Metabolite , Histone Acetyltransferase , AChR , AChE

TN1124	Neoeriocitrin		AChE
	Neoeriocitrin is a natural product isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a potent acetylcholinesterase (AChE) inhibitor.		AChE
T3769	Tenuifolin		Others , Beta-Secretase , AChE
	Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.		Others , Beta-Secretase , AChE
TN6919	Methyl tridecanoate		Beta Amyloid , AChE
	Methyl tridecanoate is a natural product.		Beta Amyloid , AChE
T6S2356	Corynoline	(+)-Corynoline	Nrf2 , AChE
	1. Corynoline ((+)-Corynoline) is an acetylcholinesterase inhibitor.		Nrf2 , AChE
T2S1720	Huperzine B		AChE
	1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy.		AChE
T4S1024	Picfeltarraenin IB		Others , AChE
	1. Picfeltarraenin IB and Picfeltarraenin IA displayes no cytotoxic activity in vitro human tumor cell line panel.		Others , AChE
T5S2343	Acetylshikonin	Acetyl shikonin	Others , P450 , AChE
	1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and ang...		Others , P450 , AChE
T11351	Galanthamine N-Oxide		AChE
	Galanthamine N-Oxide, an alkaloid extracted from Zephyranthes concolor bulbs, effectively inhibits acetylcholinesterase (AChE) from electric eel with an EC50 of 26.2 μM. It acts as a significant inhibitor of substrate ac...		AChE
T3872	Nodakenin	(+)-Marmesinin	AChE
	Nodakenin ((+)-Marmesinin) is a compound with anti-allergic and anti-inflammatory activities.		AChE
T5S1025	Picfeltarraenin IA	Picfeltarraenin A	AChE
	1. Picfeltarraenin IA (Picfeltarraenin A), IB, IV, X, XI are stronger AChE inhibitions than the known AChE inhibitor Tacrine.		AChE
Fr14127	Coumaran	2,3-Dihydrobenzofuran	Endogenous Metabolite , AChE
	Coumaran (2,3-Dihydrobenzofuran) is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara. Coumaran(2,3-Dihydrobenzofuran) can be used as a biopesticide. 2,3-dihydrobenzofuran is a member of the clas...		Endogenous Metabolite , AChE
T5S2254	Swertianolin	Bellidifolin-8-O-Glucoside	Others , HBV , Antibacterial , AChE
	1. Swertianolin (Bellidifolin-8-O-Glucoside), mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. Swertianolin...		Others , HBV , Antibacterial , AChE
T0130	Physostigmine Salicylate		AChR , AChE
	Physostigmine, a parasympathomimetic alkaloid, is a reversible cholinesterase inhibitor. It extracts from the Calabar bean.		AChR , AChE
T3026	(-)-Huperzine A	HupA,Huperzine A	Apoptosis , AChR , AChE , iGluR
	(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the tr...		Apoptosis , AChR , AChE , iGluR
T3767	Polygalacic acid	Virgaureagenin G	MMP , AChR , AChE
	Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and eleva...		MMP , AChR , AChE
T9862	Pseudocoptisine chloride	Isocoptisine chloride	AChE
	Pseudocoptisine chloride (Isocoptisine chloride) is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity (IC50 = 12.8 μ...		AChE
TN6786	O-Desmethyl Galanthamine	Sanguinine	AChE
	O-Desmethyl Galanthamine (Sanguinine) is galanthamine-type alkaloid and it is an acetylcholinesterase (AChE) inhibitor, with an IC50 1.83 μM.		AChE
T3395	Timosaponin AIII	Filiferin B,AneMarsaponin A3,Timosaponin A3	AChE , mTOR
	Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC...		AChE , mTOR
TN1030	N-p-trans-Coumaroyltyramine		AChE , Parasite
	N-p-trans-Coumaroyltyramine is a natural product, is an acetylcholinesterase (AChE) inhibitor with an an IC50 of 122 μM. N-p-trans-Coumaroyltyramine exhibits anti-trypanosomal activity with an IC50 of 13.3 μM for T. bruc...		AChE , Parasite
T5S2360	Corydaline	Corydalin,(+)-Corydaline	P450 , Virus Protease , Opioid Receptor , AChE
	1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr...		P450 , Virus Protease , Opioid Receptor , AChE
T2845	Imperatorin	Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen	TRP/TRPV Channel , AChR , AChE , NOD
	Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.		TRP/TRPV Channel , AChR , AChE , NOD
T6S0653	Linarin	Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine	TNF , AChE
	1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediat...		TNF , AChE
T0086	Galanthamine hydrobromide	Galantamine hydrobromide,Galanthamine HBr	AChR , AChE
	Galanthamine hydrobromide (Galantamine hydrobromide), a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal nicotinic ACh receptors.		AChR , AChE
T2S1200	Sinapine		Antioxidant , P-gp , AChE
	1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant and radio-protective activities.		Antioxidant , P-gp , AChE
T3933	Jatrorrhizine	Yatrorizine,neprotin	MAO , 5-HT Receptor , Antibacterial , AChE
	Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits mo...		MAO , 5-HT Receptor , Antibacterial , AChE
T2984	Scopoletin	Chrysatropic acid,Esculetin 6-methyl ether,Gelseminic acid,6-Methylesculetin	Apoptosis , AChR , AChE
	Scopoletin (Esculetin 6-methyl ether) is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).		Apoptosis , AChR , AChE
T3392	Sinapine thiocyanate		P-gp , AChE
	Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds. It is the choline ester of Sinapic Acid (S486800). It is also a phenolic-chloine conjugates, acting as anti-o...		P-gp , AChE
TN2130	Manghaslin	Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside	AChE , Glucosidase
	Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts. Manghaslin also shows inhibito...		AChE , Glucosidase
T4852	Trimyristin	Trimyristoylglycerol,Tritetradecanoin,Glyceryl trimyristate,1,2,3-Tritetradecanoylglycerol	Phosphatase , Endogenous Metabolite , AChE
	Trimyristin (Tritetradecanoin) is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ranging from yeast to humans. In humans, glyceryl trimyristate is i...		Phosphatase , Endogenous Metabolite , AChE
TN2298	Vincosamide		AChE
	Vincosamide is an alkaloid from Psychotria leiocarpa extract, inhibits the acetylcholinesterase (AChE) activity with anti-inflammatory activity. Vincosamide can effect relaxation of the supercoiled pBR322 plasmid DNA in ...		AChE
T4912	Jatrorrhizine chloride	Yatrorhizine chloride,Neprotine chloride	Others , 5-HT Receptor , OCT , Antibacterial , AChE
	Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h...		Others , 5-HT Receptor , OCT , Antibacterial , AChE
T2S0491	Isoeugenol acetate	Isoeugenyl acetate,Acetisoeugenol,Acetylisoeugenol	AChE , Antifungal
	1. Isoeugenol acetate (Acetylisoeugenol) shows good antifungal activities against R. solani and F. oxysporum. 2. Isoeugenol acetate is a mild sensitizer in vivo.		AChE , Antifungal
T4439	Sn-Glycero-3-phosphocholine	Choline Alfoscerate,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC	Endogenous Metabolite , AChE
	sn-Glycero-3-phosphocholine (Choline glycerophosphate) is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a potential for the treatment o...		Endogenous Metabolite , AChE
TN2217	Sophoflavescenol		Others , Beta-Secretase , BACE , PDE , AChR , AChE
	Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , these effects might contribute to the antitumor activity witho...		Others , Beta-Secretase , BACE , PDE , AChR , AChE
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